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Five -N'-benzylidene-N-methylpyrazine-2-carbohydrazides

Authors: Gomes, L.R.; Low, J.N.; Rodrigues, A.S.M.C. ; Wardell, J.L. ; Lima, C.H.S. ; De Souza, M.V.N.


Abstract

The compounds N‘-benzyl­idene-N-methyl­pyrazine-2-carbohydrazide, C13H12N4O, (IIa), N‘-(2-meth­oxy­benzyl­idene)-N-methyl­pyrazine-2-carbohydrazide, C14H14N4O2, (IIb), N‘-(4-cyano­benzyl­idene)-N-methyl­pyrazine-2-carbohydrazide dihydrate, C14H11N5O·2H2O, (IIc), N-methyl-N‘-(2-nitro­benzyl­idene)­pyrazine-2-carbohydrazide, C13H11N5O3, (IId), and N-methyl-N‘-(4-nitro­benzyl­idene)­pyrazine-2-carbohydrazide, C13H11N5O3, (IIe), have dihedral angles between the pyrazine rings and the benzene rings in the range 55-78°. These methyl­ated pyrazine-2-carbohydrazides have supra­molecular structures which are formed by weak C-H...O/N hydrogen bonds, with the exception of (IIc) which is hydrated. There are [pi][pi] stacking inter­actions in all five compounds. Three of these structures are compared with their nonmethyl­ated counterparts, which have dihedral angles between the pyrazine rings and the benzene rings in the range 0-6°.
Keywords: None Document Type: Research Article DOI: http://dx.doi.org/10.1107/S0108270113010056 Publication date: 17 de Abril de 2013

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