Jovem de 14 anos cria sabonete para câncer de pele e é eleito cientista do ano Leia mais em: https://forbes.com.br/forbes-tech/2023/12/jovem-de-14-a-nos-cria-sabonete-para-cancer-de-pele-e-e-eleito-cientista-do-ano/
Em entrevista à Forbes Brasil, Heman Bekele, criador de um sabonete que trata o câncer de pele e premiado pela 3M e Discovery Education, conta sua história e deixa recado para brasileiros
Descoberta bactérias que podem converter composto natural em ouro de 24 quilates
Dois cientistas da Universidade de Michigan desafiaram todas as leis da química e da microbiologia ao descobrirem uma bactéria que pode converter matéria em ouro puro. E não, não é uma piada.
Corrida por “impacto” torna academia refém de grupos editoriais
Centros de pesquisa e governos pagam bilhões de dólares a editoras de periódicos científicos por acesso a artigos cujos custos de produção, muitas vezes, eles mesmos financiaram. Decisão da Universidade de Sorbonne de afastar-se deste modelo mostra necessidade de rediscutir espiral de dependência voluntária em que a própria comunidade científica se colocou.
Current leishmaniasis drug discovery
Authors: Pinheiro, A. C.; De Souza, M. V. N. Source: Rsc Medicinal Chemistry, v. 13, p. 1029-1043, 2022 Publisher: Royal Society of Chemistry Abstract Leishmaniasis is a complex protozoan infectious disease and, associated with malnutrition, poor health services and unavailability of prophylactic control measures, neglected populations are particularly affected. Current drug regimens are outdated and […]
Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against Mycobacterium tuberculosis.
Authors: Silva, D.; Lopes, M. V. C.; Petrovski, ‘E.; Santos, M. M.; Santos, J. P.; Yamada-Ogatta, S. F.; Bispo, M. L. F.; De Souza, M. V. N.; Duarte, A. R. C.; Lourenço, M. C. S.; Gonçalves, R.S. B.; Branco, L. C. Source: Molecules, v. 27, p. 5167, 2022 Publisher: Molecules Abstract The development of novel […]
In vitro and in silico trichomonacidal activity of 2,8-bis(trifluoromethyl) quinoline analogs against Trichomonas vaginalis
Authors: Alves, M. S. D.; Sena-Lopes, Â.; Das Neves, R. N.; Casaril, A. M.; Domingues, M.; Birmann, P. T.; Da Silva, E. T.; De Souza, M. V. N.; Savehnago, L.; Borsuk, S. Source: Parasitology research, v. 121, p. 2697-2711, 2022 Publisher: Springer Abstract Trichomoniasis is a great public health burden worldwide and the increase in […]
Synthesis of primary amines from the reduction of aromatic nitro compounds through sustai-nable reaction protocols in aqueous medium
Authors: Bernardes, B.; Costa, T.; Silva, L.; Pinto, L.; Facchinetti, V.; De Souza, M. V. N; Vasconcelos, T. Source: Química Nova (Online), v. 45, p. 847-861, 2022 Publisher: Química Nova Abstract Aromatic amines are important intermediates in the industry to produce a wide array of products, and the reduction of aromatic nitro compounds is the […]
Drug repurposing of baricitinib for the treatment of Covid-19
Autores: de Souza, M. V. N.; Facchinetti, V.; Aboud, K. C. L.; da Penha, L. B.; Gomes, C. R. B. Source: Conjecturas, v. 22, p. 1657-5830, 2022 Publisher: Conjecturas Abstract The drug repurposing strategy is widely used by the pharmaceutical industry nowadays. This strategy is based on researching the potential of some marketed drugs to […]
Synthesis and antimycobacterial evaluation of fluoroquinolones derivatives coupled with isoprenyl moiety at the C-7 position
Authors:Ribeiro, C. A.; Dos Reis, D. B.; Reis, I. F.; De Carvalho, A. N.; Lourenço, M. C. S.; De Souza, M. V. N.; Pinheiro, A. C.; Saraiva, M. F. Source: Medicinal Chemistry Research, v. 31, p. 949-959, 2022 Publisher: Springer Abstract In this work, we report the synthesis and antitubercular activity of sixteen fluoroquinolones analogs […]
Crystal structure of N-(1,3-benzothiazol-2-yl)-4-iodobenzene-1-sulfonohydrazide: the unexpected importance of l N-H—π and I—π interactions on the supramolecular arrangement
Authors: Gomes, L. R.; Früchtl, H.; Low, J. N.; MOURIK, T.; Pinheiro, A. C.; De Souza, M. V. N.; Wardell, J. L. Source: Zeitschrift für anorganische und allgemeine Chemie (ZAAC), v. e, p. 1-9, 2022 Publisher: ZAAC Abstract The 2-hydrazinyl-1,3-benzothiazole derivatives are precursors for synthesis of several compounds of technological interest, including the Bt−NH−N=CHR1 (R1=alkyl, aryl, […]
Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
Authors: Chazin, E. ; Martins, L.; De Souza, M. V.; Gomes, C. R.; Da Silva, A. C.; Branco, M.; Sanchez, E.; Fuly, A.; Vasconcelos, T. Source: Journal of the Brazilian Chemical Society, v. 33, p. 2-12, 2022 Publisher: SciELO Abstract This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of ntheir ability to […]
[:pb]Experimental and computational evidence for stabilising parallel, offset π[C([double bond, length as m-dash]O)N(H)N[double bond, length as m-dash]C]⋯π(phenyl) interactions in acetohydrazide derivatives[:]
[:pb]Authors: Tan, S. L. ; Cardoso, L. N. F. ; De Souza, M. V. N. ; Wardell, S. M. S. V. ; Wardell, J. L. ; Tiekink, E. R. T. Source: CrystEngComm, v. 24, p. 962-974, 2022 Publisher: Royal Society of Chemistry Abstract Parallel, offset π[C(O)N(H)NC]⋯π(phenyl) interactions are observed in the crystal of (2-thienyl)CH2CON(H)–NC(H)Ph, along […]
