Artigos

Authors: Correia, N.R.L.; Nogueira, T.C.M.; Pinheiro, A.C.; De Souza, M.V.N.; Wardell, J.L.; Wardell, S.M.S.V. Source: Zeitschrift für Kristallographie, v. 231, p. 271-284, 2016 Publisher:  De Gruyter Abstract Structures are reported of (E)-((2-((pyridin-2-yl)hydrazonyl)methyl)arene compounds, 2-aryl-CH=N–CH)-pyridine, 8, namely (aryl=2,4-(HO)2C6H3, 8a; 2,5-(HO)2C6H3, 8b, 2–HOC6H4, 8c, as the hemihydrate, [(8c)2·

Authors: Cardoso, L.N.F.; Nogueira, T.C.M.; Kaiser, C.R.; Wardell, J.L.; Wardell, S.M.S.V.; De Souza, M.V.N. Source: Mediterranean Journal of Chemistry, v. 5(1), 356-366, 2016 Publisher: Astucia Group Abstract The synthesis and anti-tubercular activity of series of acyl hydrazonyl compounds, namely (E)-N’-(arylidene)thiophen-2-carbohydrazide, (E)- N’-(arylidene)furan-2-carbohydrazide, (E)-N-methyl- N’-arylidene-thiophen-2-carbohydrazide, and

Authors: Pinheiro, Alessandra C.; Kaiser, Carlos R.; LourenÇo, Maria C.S.; de Souza, Marcus V.N.; Wardell, Solange M.S.V.; Wardell, James L. Goncalves, R.S.B.; De Souza, M.V.N.; Wardell, S.M.S.V.; Wardell, J.L. Source: Zeitschrift für Kristallographie, v. 231(1), p. 35–46, 2016 Publisher: De Gruyter Abstract The reaction between racemic erythro [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol] and 2-formyl-5-nitrothiene

Authors: Amim, R.S.; Firmino, G.S.S.; Rego, A.C.P.D.; Nery, A.L.; Da Silva, S.A.G.; De Souza, M.V.N.; Pessoa, C.; Resende, J.A.L.C.; Figueroa-Villar, J.D.; Lessa, J.A. Source: J. Braz. Chem. Soc., v. 27(4), p.769-777, 2016   Publisher: Sociedade Brasileira de Química Abstract The isoniazid-derived hydrazones 2-pyridinecarbaldehyde- (HPCIH), 2-acetylpyridine-

Authors: Facchinetti, V.; Avellar, M.M.; Nery, A.C.S.; Gomes, C.R.B.; Vasconcelos, T.R.A.; De Souza, M.V.N. Source: Synthesis, v.48(3), p.437-440, 2016 Publisher: Thieme Abstract Reactions proceed to completion in a few seconds and products are obtained in moderate to excellent yields after easy workup. Moreover, the synthesis

[:pb] Authors: Pinto, L.S.S.; Silva, E.T.; Kaiser, C.R.; De Souza, M.V.N.; Wardell, S.M.S.V.; Wardell, J.L. Source:  Letters in Organic Chemistry, v. 13, p. 1-1, 2016. Publisher: Bentham Science Abstract The isoniazid has been a key compound in first-line tuberculosis (TB) treatment, usually in combination with

Authors: Silva, E.T.; Araújo S.A.; Moraes, A.M.; Souza, L.A.; Lourenço, M.C.; De Souza, M.V.N.; Wardell, J.L.; Wardell, S.M.S.V. Source: Scientia Pharmaceutica, v. 84, p. 467-483, 2016 Publisher: Austrian Pharmaceutical Society Abstract Both sonochemical and classical methodologies have been employed to convert camphor, 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one, C9H16C=O, into a number

Authors: Pinheiro, A.C.; Mendonça, T.C.M.; De Souza, M.V.N. Source: Anti-Cancer Agents in Medicinal Chemistry, v. 16, p. 1339-1352, 2016 Publisher: Bentham Science Abstract Heterocyclic compounds are a class of substances, which play a critical role in modern drug discovery being incorporated in the structure of a

Authors:  Cardoso, L.N.F.; Nogueira, T.C.M.; Wardell, J.L.; Wardell, S.M.S.V.; De Souza, M.V.N.; Jotani, M.M.; Tiekink, E.R.T. Source: Acta Crystallographica Section E Crystallographic Communications, v. 72, p. 1025-1031, 2016 Publisher: International Union of Crystallography Abstract In the title carbohydrazide, C10H7N3O4S, the dihedral angle between the terminal

Authors: Lima, C.H.S.; De Alencastro, R.; Kaiser, C.R.; De Souza, M.V.N.; Rodrigues, C.; Albuquerque, M. Source:  International Journal of Molecular Sciences (Online), v. 16, p. 23695-23722, 2015. Publisher: Multidisciplinary Digital Publishing Institute (MDPI) Abstract Molecular dynamics (MD) simulations of 12 aqueous systems of the NADH-dependent

Authors: Bispo, M.L.F.; Alcântara, C.C.; Moraes, M.O.; Pessoa, C.O.; Rodrigues, F.A.R.; Kaiser, C.R.; Wardell, S.M.S.V.; Wardell, J.L.; De Souza, M.V.N. Source: Monatshefte fur Chemie, v. 146, p. 2041-2052, 2015 Publisher: Springer International Publishing AG   Abstract A new class of 4-quinolinylhydrazone derivatives has been synthesized

Authors: Nogueira, T.C.M.; Pinheiro, A.C.; Wardell, J.L.; De Souza, M.V.N.; Abberley, J.P.; Harrison, W.T.A. Source: Acta Crystallographica Section C Structural Chemistry, v. 71, p. 1-10, 2015 Publisher: International Union of Crystallography Abstract Oxazolidin-2-ones are widely used as protective groups for 1,2-amino alcohols and chiral derivatives