Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes

Authors: Chazin, E.L.; Martins, L.B.; De Souza, M.V.N.; Gomes, C.R.B.; Da Silva, A.C.R.; Branco, M.C.; Sanchez, E.F.; Fuly, A.L.; Vasconcelos, T.R.A. Source: J. Braz. Chem. Soc., v. 33(1), p. 2-12, 2022 Publisher: Sociedade Brasileira de Química Abstract This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of their ability to inhibit some in […]

Crystal structure of N-(1,3-benzothiazol-2-yl)-4-iodobenzene-1-sulfonohydrazide: the unexpected importance of l N-H—π and I—π interactions on the supramolecular arrangement

Authors: Gomes, L.R.; Früchtl, H.; Low, J.N.; Van Mourik, T.;Pinheiro, A.C.; De Souza, M.V.N.; Wardell, J.L. Source:  Zeitschrift für anorganische und allgemeine Chemie, v. 648(17), p. e202200087, 2022 Publisher: Wiley   Abstract The 2-hydrazinyl-1,3-benzothiazole derivatives are precursors for synthesis of several compounds of technological interest, including the Bt−NH−N=CHR1 (R1=alkyl, aryl, heteroaryl), derivatives. Usually when Bt−NH−NH2 is […]