Synthetic Applications of 3-Amino-5-Piperidein-2-ones: Synthesis of Methionine-Derived Peptidomimetics
Authors: De Souza, M.V.N.; Rubiralta, M.; Diez, A.; Dodd, R.H.; Rio, X.; Estiarte, A. Source: Tetrahedron (Oxford), EUA, v. 55, p. 10173-10186, 1999. Publisher: Elsevier Abstract A method is described for the efficient preparation of 3-amino-Δ5-piperidein-2-ones3. A synthetic application of enamides 3 has been achieved by methylthiolation on the C5 position to obtain the target […]