Biological Activity and Synthetic Metodologies for the Preparation of Fluorquinolones, A Class of Potent Antibacterial Agents
Authors: De Souza, M.V.N.; Almeida, M.V.; Couri, M.R.C.; Silva, A.D. Source: Current Medicinal Chemistry, v. 10, n.1, p. 21-40, 2003. Publisher: Bentham Science Abstract In this present review we report different synthetic methodologies for the preparation of fluoroquinolones and their biological properties. The appearance of the fluoroquinolones, a new class of antibacterial agents (based on […]
Synthesis of Platinum Complexes from N-Benzyl-2-Aminoethanethiol Derivatives
Authors: De Souza, M.V.N.; Almeida, M.V.; Oliveira, L.L.C. Source: The Scientific World Journal, v. 3, p. 348-353, 2003. Publisher: Hindawi Publishing Corporation Abstract Twelve new platinum(II) complexes, analogs of cisplatin, containing a 2-aminoethanethiol N-substituted by several benzyl groups have been prepared and characterized in good yields. The ligands were obtained by reaction between 2-aminoethanethiol hydrochloride […]
