ynthesis of 2,3-Dihydrofuro[3,2-c]pyridine-3,4-dicarboxylic Acid, a Conformationally Constrained Analogue of the Subtype Selective NMDA Receptor Agonist Homoquinolinic Acid

Authors: De Souza, M.V.N.; Yan, Z. ; Dodd, R. H. Source: Heterocycles, v. 64, p. 261, 2004. Publisher: The Japan Institute of Heterocyclic Chemistry Publications Abstract 4-Allyloxy- and 4-prop-2-ynyloxy-3-iodopicolinic acid derivatives, obtained by reaction of 4-chloro-2-iodopicolinanilides (11,14) with the sodium salts of allyl alcohol and propargyl alcohol, respectively, were subjected to tri-n-butyltin hydride/AIBN free radical cyclization […]