Cyclisation of 2-chloro-N-(2-pyridinyl)nicotinamides to 5-oxo-5,6-dihydrodipyrido[1,2-a:3â ,2â -e]pyrimidin-11-ium chlorides
Authors: De Souza, M.V.N.; Fernandes, E.L.; Pais, K.C.; Vasconcelos, T.A.; Wardell, S.M.S.V.; Wardell, J.L. Source: Journal of Chemical Research. Synopses (Print), v. 2006, p. 93-97, 2006. Publisher: Science Reviews 2000 Ltd. Abstract The ease of thermal cyclisation of 2-chloro-N-(R-2-pyridinyl)nicotinamides, (5: X = NH) to 5-oxo-5,6-dihydrodipyrido-[1,2-a:3‘,2‘-e]pyrimidin-11-ium chlorides in solution has been found to be in the order: […]
