Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action
Authors: Costa, J.C.S.; Neves, J.S.; De Souza, M.V.N.; Siqueira, R.A.; Romeiro, N.C.; Boechat, N.; Silva, P.M.; Martins, M.A. Source: Bioorganic & Medicinal Chemistry Letters, v. 18, p. 1162-1166, 2008. Publisher: Elsevier Abstract The present structure-activity relationship (SAR) study focused on chemical modifications of the structure of the local anesthetic lidocaine, and indicated analogues having reduced […]
