Mefloquine derivatives: Crystal structures and anti-tubercular activities of diphenyl[((R,S)-2,8-bis(trifluoromethyl)quinolin-4-yl)-piperidin-2-yl-methanolato-O,N]boron and (±)-erythro-mefloquinium tetraphenylborate solvates
Authors: Wardell, J.L.; De Souza, M.V.N.; Wardell, S.M.S.V.; Lourenço, M.C.S. Source: Journal of Molecular Structure (Print), p. 67-74, 2011. Publisher: Elsevier Abstract Thermolysis of (R*,S*)-(2-{[2,8-bis(trifluoromethyl)quinolin-4-yl](hydroxy)∼methyl}piperidin-1-ium) tetraphenylborate, (±)-erythro-mefloquinium tetraphenylborate, 3, in solution or neat, provides the oxazaborolidine derivative, diphenyl[(R*,S*)-(2,8-bis(trifluoromethyl)quinolin-4-yl)]piperidin-2-yl-methanolato-O,N]boron, 2. Crystal structures of solvates of 2 and 3 are reported. As shown by the 1H NMR […]
