Novel thalidomide analogues from diamines inhibit pro-inflammatory cytokine production and CD80 expression while enhancing IL-10.
Authors: Mazzoccoli, L.; Cardoso, S.H.; Amarante, G.W.; De Souza, M.V.N.; Domingues, R.; Machado, M.A.; Almeida, M.V.; Teixeira, H.C. Source: Biomedicine & Pharmacotherapy, v. 1, p. 1-10, 2012. Publisher: Elsevier Abstract Thalidomide is used to treat a variety of diseases including erythema nodosum leprosum, an inflammatory complication of leprosy. However, this drug has severe teratogenic activity […]
