Synthesis and Antitubercular Evaluation of N -Arylpyrazine and N,N -Alkyl-diylpyrazine-2-carboxamide Derivatives
Authors: Bispo, M.L.F.; Gonçalves, R.S.B.; Lima, C.H.S.; Cardoso, L.N.F.; Lourenço, M.C.S.; DE Souza, M.V.N. Source: Journal of Heterocyclic Chemistry, v. 49, p. 1317-1322, 2012. Publisher: John Wiley & Sons, Inc. Abstract Two series of pyrazinamide (PZA) derivatives have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv. Some compounds exhibited […]
