Optimization of an Electrolyte System for the Simultaneous Separation of Nelfinavir Mesylate and Two Impurities by Micellar Electrokinetic Chromatography

Authors: Bastos, C.A.; Gomes, C.R.B.; De Souza, M.V.N.; Oliveira, M.A.L. Source:  Journal of the Brazilian Chemical Society (Impresso), v. 26, p. 887-898, 2015 Publisher: Brazilian Chemical Society Abstract A methodology for the simultaneous determination of nelfinavir mesylate and the impurities 3-hydroxy-2-methylbenzoic acid and (2R,3R)-4-((3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-(phenylthio)butan-2-aminium benzoate by micellar electrokinetic chromatography, with an analysis time of 25 […]