Synthesis and evaluation of copper(II) complexes with isoniazid-derived hydrazones as anticancer and antitubercular agents.

Authors: Firmino, G.S.S.; De Souza, M.V.N.; Pessoa, C.O.;  Lourenço, M.C.S.; Resende, J.A.L.C.; Lessa, J.A. Source: BioMetals (Oxford), v. 29, p. 953-963, 2016. Publisher: Springer Science Abstract In this study, the N,N,O metal chelator 2-pyridinecarboxaldehydeisonicotinoyl hydrazone (HPCIH, 1) and its derivatives 2-acetylpyridine-(HAPIH 2), 2-pyridineformamide-(HPAmIH, 3) and pyrazineformamide-(HPzAmIH, 4) were employed in the synthesis of four copper(II) […]