Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
Authors: Chazin, E. ; Martins, L.; De Souza, M. V.; Gomes, C. R.; Da Silva, A. C.; Branco, M.; Sanchez, E.; Fuly, A.; Vasconcelos, T. Source: Journal of the Brazilian Chemical Society, v. 33, p. 2-12, 2022 Publisher: SciELO Abstract This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of ntheir ability to […]
[:pb]Experimental and computational evidence for stabilising parallel, offset π[C([double bond, length as m-dash]O)N(H)N[double bond, length as m-dash]C]⋯π(phenyl) interactions in acetohydrazide derivatives[:]
[:pb]Authors: Tan, S. L. ; Cardoso, L. N. F. ; De Souza, M. V. N. ; Wardell, S. M. S. V. ; Wardell, J. L. ; Tiekink, E. R. T. Source: CrystEngComm, v. 24, p. 962-974, 2022 Publisher: Royal Society of Chemistry Abstract Parallel, offset π[C(O)N(H)NC]⋯π(phenyl) interactions are observed in the crystal of (2-thienyl)CH2CON(H)–NC(H)Ph, along […]
[:pb]Camphor nitroimine: a key building block in unusual transformations and its applications in the synthesis of bioactive compounds[:]
[:pb] Authors: Silva, E.T.; Santos, L. S.; Andrade, G. F.; Rosa, E. J. R.; De Souza, M. V. N. Source: Molecular Diversity, v. 26, p. 3463-3483, 2022 Publisher: Springer Abstract The development of new drugs requires a lot of time and high financial investments. It involves a research network in which there is the participation […]
