Authors: De Souza, M.V.N.; Rubiralta, M.; Diez, A.; Dodd, R.H.; Rio, X.; Estiarte, A.
Source: Tetrahedron (Oxford), EUA, v. 55, p. 10173-10186, 1999.
Publisher: Elsevier
Abstract
A method is described for the efficient preparation of 3-amino-Δ5-piperidein-2-ones3. A synthetic application of enamides 3 has been achieved by methylthiolation on the C5 position to obtain the target methionine-derived pseudopeptides 2.Keywords: peptide mimetics; enamides; lactams; piperideinones Document Type: Research Article DOI: http://dx.doi.org/10.1016/S0040-4020(99)00545-1 Publication date: 13 de Agosto de 1999
