Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents
Authors: Vicente, F.R.C.; Lourenço, M.C.; Henriques, M.G.M.O.; Candea, A.L.P.; Gonçalves, R.S.B.; Nogueira, T.C.M.; Ferreira, M.L.; De Souza, M.V.N. Source: Bioorganic & Medicinal Chemistry Letters, v. 17, p. 6895-6898, 2007. Publisher: Elsevier Abstract The present article describes a series of 21 N-(aryl)-2-thiophen-2-ylacetamides, which were synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis, […]
