Synthesis of Novel Ethyl (substituted)phenyl-4-oxothiazolidin-3-yl)-1-ethyl-4-oxo-1,4-dihydroquinoline-3-Carboxylates as Potential Anticancer Agents
Authors: Facchinetti, V.; Guimarães, F.A.; De Souza, M.V.N.; Gomes, C.R.B.; De Souza, M.C.B.V.; Wardell, J.L.; Wardell, S.M.S.V.; Vasconcelos, T.R.A. Source: Journal of Heterocyclic Chemistry, v. 52, p. 1245-1252, 2015 Publisher: John Wiley & Sons, Inc. Abstract A series of ethyl (substituted)phenyl-4-oxothiazolidin-3-yl)-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylates () has been prepared from reactions between aminoquinolones with arenealdehydes and mercaptoacetic acid. The critical […]
Synthesis and antitubercular evaluation of 7-chloro-4-alkoxyquinoline derivatives
Authors: Bispo, M.L.F.; Cardoso, L.N.F.; Lourenço, M.C.S.; Bezerra, F.A.F.M.; Soares, R.P.P.; Bertollo, C.M.; De Souza, M.V.N. Source: Mediterranean Journal of Chemistry, v. 4, p. 1-8, 2015. Publisher: Med Journal Editions Abstract A series of eight 7-chloro-4-alkoxyquinoline derivatives (2a-h) have been synthesized and their in vitro (antimycobacterial) activity against Mycobacterium tuberculosis was evaluated. Furthermore, all the […]
