[:pb]Synthesis of PJOV56, a new quinoxalinyl-hydrazone derivative able to induce autophagy and apoptosis in colorectal cancer cells, and related compounds[:]

[:pb]Authors: Maranhão, S.S.; Moura, A. F.; Oliveira, A. C. A.; Lima, D. J. B.; Barros-Nepomuceno, F. W. A.; Paier, C. R. K.; Pinheiro, A. C.; Nogueira, T. C. M.; De Souza, M. V. N.; Pessoa, C. Source: Bioorganic & Medicinal Chemistry Letters, v. 30, p. 126851-126851, 2020. Publisher: ScienceDirect Abstract Quinoxaline derivatives are reported as […]

[:pb]Multigram-scale synthesis of building block nitro-imine derivative by using classical method and ultrasound irradiation and conversion to imino-alcohol derivative, using Camphor as starting material. [:]

[:pb]Authors: Da Silva, E. T. ; Da Silva, A. A. ; Moraes, A. M. ; De Souza, M. V. N. Source: Letters in Organic Chemistry, v. 17, p. 165-169, 2020 Publisher: Bentham Science Publishers Abstract This study describes a simple multigram-scale procedure for the preparation of (E)-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene)nitramide, nitro-imine 2, by using both classical methods and […]