[:pb]Authors: Da Silveira, L. S. P.; Vasconcelos, T. R. A. ; Gomes, C. R. B. ; De Souza, M. V. N.
Source:Current Organic Chemistry, v. 24, p. 473-486, 2020
Publisher: Bentham science
Abstract
Azetidin-2-ones (β-lactams) and its derivatives are an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, anticancer, anti-diabetic, anti-inflammatory and anticonvulsant. Efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side effects. The present review aimed to highlight some recent discoveries (2013-2019) on the development of novel azetidin-2-one-based compounds as potential anticancer agents.
Keywords: Azetidin-2-ones, β-lactams, biological activity, cancer, drugs, heterocycles
Document Type: Research Article
DOI: 10.2174/1385272824666200303115444
Publication date: 17 de maio de 2020[:]
