Search
Close this search box.

An eco-friendly, Hantzsch-Based, solvent-free approach to 2-aminothiazoles and 2-aminoselenazoles

Authors: Facchinetti, V.; Avellar, M.M.; Nery, A.C.S.; Gomes, C.R.B.; Vasconcelos, T.R.A.; De Souza, M.V.N.


Abstract

Reactions proceed to completion in a few seconds and products are obtained in moderate to excellent yields after easy workup. Moreover, the synthesis of 4-(2-amino-1,3-selenazol-4-yl)benzonitrile hydrobromide is reported for the first time.
Keywords: thiazoles – 1,3-selenazoles – synthesis – solvent-free – heterocycles Document Type: Research Article DOI: http://dx.doi.org/10.1055/s-0035-1560534 Publication date: 1 de Janeiro de 2016 [:en]

Abstract

Reactions proceed to completion in a few seconds and products are obtained in moderate to excellent yields after easy workup. Moreover, the synthesis of 4-(2-amino-1,3-selenazol-4-yl)benzonitrile hydrobromide is reported for the first time.


Keywords: thiazoles – 1,3-selenazoles – synthesis – solvent-free – heterocycles Document Type: Research Article DOI: http://dx.doi.org/10.1055/s-0035-1560534 Publication date: 1 de Janeiro de 2016

Compartilhar publicação

Facebook
Twitter
Email
LinkedIn
WhatsApp

Deixe seu comentário

Compartilhar

Sobre a SSCDT

Nosso grupo de pesquisa está situado em Farmanguinhos e atualmente é o maior laboratório farmacêutico oficial vinculado ao Ministério da Saúde. Farmanguinhos produz mais de um bilhão de medicamentos por ano para os programas estratégicos do Governo Federal, além de atender demandas emergenciais no Brasil e no exterior.

posts Recentes