Search
Close this search box.

[:pb]Microwave-Assisted Synthesis of Quinoxalines – A Review[:]

[:pb]Authors: De Souza, M. V. N.; Gomes, C. R. B.; Facchinetti, V.
Source: Current Microwave Chemistry, v. 04, p. 277-286, 2017
Publisher: Bentham Science


Abstract

Background: Quinoxaline is an important nucleus used in the development of novel potentially bioactive structures. Hence, the development of new methodologies that provide access to this scaffold in shorter times and increased yields is of interest. In this work, we review many interesting microwave-assisted methodologies for the synthesis of quinoxalines reported from 2007 to 2015.

Methods: The most prominent methods for the synthesis of quinoxalines under microwave irradiation published in articles from 2007-2015 are reviewed.

Conclusion: Microwave irradiation proved to be a useful tool, providing many advantages on the synthesis of this class, such as shorter reaction times, higher yields and better selectivity, when compared to classical procedures.


Keywords: catalysis, drugs, green chemistry, microwave, quinoxaline, synthesis

Document Type: Review Article

DOI: 10.2174/2213335604666171010153416

Publication date: 1 de Dezembro de 2017

 [:]

Compartilhar publicação

Facebook
Twitter
Email
LinkedIn
WhatsApp

Deixe seu comentário

Compartilhar

Sobre a SSCDT

Nosso grupo de pesquisa está situado em Farmanguinhos e atualmente é o maior laboratório farmacêutico oficial vinculado ao Ministério da Saúde. Farmanguinhos produz mais de um bilhão de medicamentos por ano para os programas estratégicos do Governo Federal, além de atender demandas emergenciais no Brasil e no exterior.

posts Recentes