Source: Mini-Reviews in Medical Chemistry, v. 12, p. 866-874, 2012. Publisher: Bentham Science
Quinolones and its derivatives comprise an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, antitumor, antiviral, anti-ischemic, antiparasitic and anxiolytic. Persistent efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side-effects. The present review aims to highlight some recent discoveries on the development of novel quinolone-based compounds with potential antitubercular and anticancer activity.
Biological activity, cancer, drugs, quinolones, tuberculosis, iodoanilines, BCG, Ciprofloxacin, in vitro, 6-nitroquinolonesDocument Type:
: 1 de Janeiro de 2012