[:pb]Authors: Pinto, L. S. S.; Couri, M. R. C.; De Souza, M. V. N.
Source: Current Organic Synthesis, v. 15, p. 21-37, 2018
Publisher: Bentham Science
Abstract
Background: Coumarin is an important class of natural products with applications in different areas of knowledge. Due to its importance, several methodologies and strategies have been developed for the synthesis of different classes of compounds containing this nucleus.
Objective: The aim of this review is to cover in the last five years the complex fused coumarin derivatives synthesized in one-pot three-component reactions.
Conclusion: Considering that multicomponent reactions are a powerful tool to produce simple and complex compounds in one or few steps with high selectivity and yields while following the green chemistry principles.
Keywords: coumarins, green chemistry, multicomponent reactions, natural products, synthesis, derivatives
Document Type: Review Article
DOI: 10.2174/1570179414666170614124053
Publication date: 2018
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