[:pb]Efficacy of the 7-chloro-4-(3-hydroxy-benzilidenehydrazo)quinoline derivative against infection caused by Leishmania amazonensis[:]
[:pb]Authors: Antinarelli, L. M. R. ; De Souza, M. V. N.; Coelho, E. A. F. ; Lima, W. P. ; Coimbra, E. S. Source: Sociedade Brasileira De Medicina Tropical, v. 53, p. 1-5, 2020 Publisher: Revista da Sociedade Brasileira de Medicina Tropical Abstract Introduction: The drugs currently available for leishmaniasis treatment have major limitations. Methods: […]
[:pb]Augmented Reality in Drug Package: a Promising Strategy against Non-adherence in the Treatment of Tuberculosis[:]
[:pb]Authors: De Oliveira, D. E.; De Souza, M. V. N.; Barroso, W. B. G. Source: Medicine Research, v. 4, p. 200007-200007, 2020 Publisher: Medicine Research Abstract Augmented reality is a technology-based on an interaction between the virtual and real-world, mixing them and expanding their possibilities. This technology is currently used in the most varied areas […]
[:pb]Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses[:]
[:pb]Authors: Alves, M. S. D. ; Das Neves, R. N. ; Sena-Lopes, Â. ; Domingues, M. ; Casaril, A. M. ; Segatto, N. V. ; Nogueira, T. C. M. ; De Souza, M. V. Nora ; Savegnago, L.; Seixas, F. K. ; Collares, T. ; Borsuk, S. Source: Parasites & Vectors, v. 13, p. 59-72, […]
[:pb]A Brief Review on the Development of Novel Potentially Active Azetidin-2-ones Against Cancer[:]
[:pb]Authors: Da Silveira, L. S. P.; Vasconcelos, T. R. A. ; Gomes, C. R. B. ; De Souza, M. V. N. Source:Current Organic Chemistry, v. 24, p. 473-486, 2020 Publisher: Bentham science Abstract Azetidin-2-ones (β-lactams) and its derivatives are an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as […]
[:pb]Response of preantral follicles exposed to quinoxaline: A new compound with anticancer potential[:]
[:pb]Authors: Guerreiro, D. D.; De Lima, L. F.; De Sá, N. A. R.; Mbemya, G. T.; Ferreira, A. C. A.; Alves, B. G.; Sant’anna, S. M.; Pessoa, C.; Pinheiro, A. C.; Nogueira, T. C. M.; De Souza, M. V. N.; De Figueiredo, J. R.; Rodrigues, A. P. R. Source: Research In Veterinary Science, v. 128, […]
[:pb]Synthesis of PJOV56, a new quinoxalinyl-hydrazone derivative able to induce autophagy and apoptosis in colorectal cancer cells, and related compounds[:]
[:pb]Authors: Maranhão, S.S.; Moura, A. F.; Oliveira, A. C. A.; Lima, D. J. B.; Barros-Nepomuceno, F. W. A.; Paier, C. R. K.; Pinheiro, A. C.; Nogueira, T. C. M.; De Souza, M. V. N.; Pessoa, C. Source: Bioorganic & Medicinal Chemistry Letters, v. 30, p. 126851-126851, 2020. Publisher: ScienceDirect Abstract Quinoxaline derivatives are reported as […]
[:pb]Synthesis and SAR study of simple aryl oximes and nitrofuranyl derivatives with potent activity against Mycobacterium tuberculosis[:]
[:pb]Authors: Da Costa, C. F.; De Souza, De Souza, M. V. N.; Da Silva, M. C. L.; COIMBRA, E. S.; Da Silva, G. L. C.; Wardell, J.; Calixto, S. L.; Da Trindade, J. G. […]
[:pb]Multigram-scale synthesis of building block nitro-imine derivative by using classical method and ultrasound irradiation and conversion to imino-alcohol derivative, using Camphor as starting material. [:]
[:pb]Authors: Da Silva, E. T. ; Da Silva, A. A. ; Moraes, A. M. ; De Souza, M. V. N. Source: Letters in Organic Chemistry, v. 17, p. 165-169, 2020 Publisher: Bentham Science Publishers Abstract This study describes a simple multigram-scale procedure for the preparation of (E)-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene)nitramide, nitro-imine 2, by using both classical methods and […]
[:pb]Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches[:]
[:pb]Authors: Rebello, K. M.; Andrade-Neto, V. V.; Gomes, C. R. B.; De Souza, M. V. N.; Branquinha, M. H.; Santos, A. L. S.; Torres-Santos, E. C.; D’avila-Levy, C. M. Source: Frontiers in Cellular and Infection Microbiology, v. 9, p. 1-8, 2019 Publisher: Frontiers Media Abstract Concurrently, leishmaniasis and AIDS are global public health issues and […]
[:pb]Antibiofilm Potential of Arenecarbaldehyde 2-Pyridinylhydrazone Derivatives Against Acinetobacter baumannii[:]
[:pb]Authors: Halicki, P. C. B.; Radin, V.; Von Groll, A.; De Souza, M. V. N.; Pinheiro, A. C.; Da Silva, P. E. A. ; Ramos, D. F. Source: Microbial Drug Resistance, v. 26, p. 1429-1436, 2019 Publisher: Mary Ann Liebert Abstract In the last 15 years, Acinetobacter baumannii has received special attention, mainly due to several resistance […]
[:pb]Crystal structures, Hirshfeld surface analysis and Pixel energy calculations of three trifluoromethylquinoline derivatives: further analyses of fluorine close contacts in trifluoromethylated derivatives[:]
[:pb]Authors: Gomes, L. R.; Da Silva, E. T.; De Souza, M. V.N.; Wardell, J. L.; Low, J. N. Source: Zeitschrift Fur Naturforschung Section B-A Journal Of Chemical Sciences, v. 74, p. 791-810, 2019 Publisher: De Gruyter Abstract As many studies have revealed, the introduction of a CF3 group into an organic compound can result in significant […]
[:pb]Different packing motifs mediated by weak interactions and polymorphism in the crystal structures of five 2-(benzylidene)benzosuberone derivatives[:]
[:pb]Authors: Seaman, L. S.; Costa, C. F.; De Souza, M. V. N.; Wardell, S. M. S. V. ; Wardell, J. L. ; Harrison, W. T. A. Source: Acta Crystallographica Section e, Crystallographic Communications, v. 75, p. 1741-1747, 2019 Publisher: Science Direct Abstract The syntheses and crystal structures of five 2-benzylidene-1-benzosuberone [1-benzosuberone is 6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one] derivatives, viz. 2-(4-methoxybenzylidene)-1-benzosuberone, C19H18O2, […]
