(Pyrazinecarbonyl)hydrazones of heteroarenealdehydes: crystal structures formed from N—H···O, N—HN, C—H···O hydrogen-bonds, C—H···π and π···π interactions
Authors: Howie, R.A.; Lima, C.H.S.; Kaiser, C.R.; Silva, M.M.; De Souza, M.V.N.; Wardell, J.L.; Wardell, S.M.S.V. Source: Zeitschrift für Kristallographie, v. 225, p. 245-252, 2010. Publisher: De Gruyter Abstract The molecules of the (pyrazinecarbonyl)hydrazones of the heterocyclic aldehydes RCHO with R = pyrrol-2-yl, furan-2-yl, thien-2-yl and pyridin-2-yl corresponding to compounds (2: X = NH), (2: […]
Synthesis and antitubercular evaluation of new fluoroquinolone derivatives coupled with carbohydrates
Authors: Saraiva, M.F.; De Souza, M.V.N.; Tran Huu Dau, M.E.; Araújo, D.P.; Carvalho, G.S.G.; Almeida, M.V. Source: Carbohydrate Research (Chicago, Ill.. Print), v. 345, p. 761-767, 2010. Publisher: Elsevier Abstract We describe in this work the synthesis of nine new fluoroquinolone derivatives based on modifications at the C-7 position of the known fluoroquinolones cipro-, gati-, […]
Structures of (pyrazinecarbonyl)hydrazones of substituted benzaldehydes: supramolecular arrangements generated by various intermolecular contacts
Authors: Howie, R.A.; Lima, C.H.S.;Kaiser, C.R.; De Souza, M.V.N.; Wardell, J.L.; Wardell, S.M.S.V. Source: Zeitschrift für Kristallographie, v. 225, p. 19-28, 2010. Publisher: De Gruyter Abstract The crystal structures of seven (pyrazinecarbonyl)hydrazone mono-substituted benzaldehyde derivatives, N2C4H3CONHN=CHC6H4X (1: X = CN, OMe, OEt or NO2) are reported. In all cases extensive intermolecular C–H · · · […]
Structures of (pyrazinecarbonyl)hydrazones of substituted benzaldehydes: different supramolecular arrangements from C H•••X (X = O, N, ?) hydrogen bonds
Authors: Howie, R.A.; Lima, C.H.S.; Kaiser, C.R.; De Souza, M.V.N.; Wardell, J.L.; Wardell, S.M.S.V. Source: Zeitschrift für Kristallographie, v. 225, p. 158-166, 2010. Publisher: De Gruyter Abstract The crystal structures of six (pyrazinecarbonyl)hydrazone di-substituted benzaldehyde derivatives [N2C4H3CONHN = CHC6H3XY: X,Y = 2,3-Cl2; 2,3-(MeO)2; 2,4-F2; 2,4-Me2; 3-HO—4-MeO; 3-MeO—4-HO] and one tri-substituted benzaldehyde derivative, [N2C4H3CONHN = CHC6H2X3: X3 […]
Synthesis, Cytotoxicity and Antileishmanial Activity of Some N-(2-(indol-3-yl)ethyl)-7-chloroquinolin-4-amines
Authors: Coimbra, E.S.; Carvalhaes, R.; Grazul, R.M.; Machado, P.A.; De Souza, M.V.N.; Da Silva, A.D. Source: Chemical Biology & Drug Design (Print), v. 75, p. 628-631, 2010. Publisher: John Wiley & Sons, Inc. Abstract We report herein the condensation of 4,7-dichloroquinoline (1) with tryptamine (2) and D-tryptophan methyl ester (3). Hydrolysis of the methyl ester adduct […]
Fast determination of ethambutol in pharmaceutical formulations using capillary electrophoresis with capacitively coupled contactless conductivity detection.
Authors: Da Silva, J.A.F.; De Castro, N.V.; De Jesus, D.P.; Faria, A.F.; De Souza, M.V.N.; Oliveira, M.A.L. Source: Electrophoresis (Weinheim. Print), v. 31, p. 570-574, 2010. Publisher: John Wiley & Sons, Inc. Abstract A method for the determination of ethambutol (EMB), a first-line drug against tuberculosis, based on CE with capacitively coupled contactless conductivity detection […]
7-Chloro-4-[( E )-2-(2-methoxybenzylidene)hydrazin-1-yl]quinoline monohydrate
Authors: De Souza, M.V.N.; Howie, R.A.; Tiekink, E.R.T.; Wardell, J.L.; Wardell, S.M.S.V.; Kaiser, C.R. Source: Acta Crystallographica. Section E, v. 66, p. 698-699, 2010 Publisher: International Union of Crystallography Abstract In the title hydrate, C17H14ClN3O·H2O, the dihedral angle between the quinoline fused-ring system and the benzene ring is 13.4 (2)° and the conformation about the C=N […]
2-Bromopyridine-3-carboxylic acid
Authors: Howie, R. A.; Gonçalves, R.S.; De Souza, M.V.N.; Tiekink, E.R.T.; Wardell, J.L. Source: Acta Crystallographica. Section E, v. 66, p. 486-486, 2010. Publisher: International Union of Crystallography Abstract The carboxylic acid residue in the title compound, C6H4BrNO2, is twisted out of the plane of the other atoms, as indicated by the (Br)C-C-C-Ocarbonyl torsion angle […]
(2 E )- N -Benzoyl-3-(4-nitrophenyl)prop-2-enohydrazide
Authors: Carvalho, S.A.; Silva, E.F.; De Souza, M.V.N.; Tiekink, E.R.T.; Wardell, J.L.; Wardell, S.M.S.V. Source: Acta Crystallographica. Section E, v. 66, p. 150-151, 2010. Publisher: International Union of Crystallography Abstract In the title compound, C16H13N3O4, the dihedral angle between the terminal benzene rings is 14.02 (7)°. The carbonyl groups are anti with respect to each other, which […]
7-Chloro-4-[( E )- N -(4-fluorobenzylidene)hydrazinyl]quinoline monohydrate
Authors: De Souza, M.V.N.; Howie, R.A.; Wardell, J.L.; Wardell, S.M.S.V.; Tiekink, E.R.T. Source: Acta Crystallographica. Section E, v. 66, p. 152-153, 2010. Publisher: International Union of Crystallography Abstract The molecule of the title hydrate, C16H11ClFN3·H2O, is slightly twisted, as indicated by the dihedral angle of 9.55 (10)° formed between the quinoline ring system and the benzene ring. […]
N-(4-Bromophenyl)-2-(2-thienyl)acetamide
Authors: Nogueira, T.C.M.; De Souza, M.V.N.; Wardell, J.L.; Wardell, S.M.S.V.; Tiekink, E.R.T. Source: Acta Crystallographica. Section E, v. 66, p. 177-177, 2010. Publisher: International Union of Crystallography Abstract The thienyl ring in the title compound, C12H10BrNOS, is disordered over two diagonally opposite positions, the major component having a site-occupancy factor of 0.660 (5). The molecule is […]
N-[(E)-2,6-Dichlorobenzylidene]pyrazine-2-carbohydrazide.
Authors: Howie, R. A.; De Souza, M.V.N.; Wardell, S.M.S.V.; Wardell, J.L. ; Tiekink, E.R.T.; De Souza, M.V.N. Source: Acta Crystallographica. Section E, v. 66, p. 178-179, 2010. Publisher: International Union of Crystallography Abstract The title compound, C12H8Cl2N4O, is non-planar, the dihedral angle formed between the pendant pyrazine and benzene rings being 12.55 (11)°. An intramolecular N-HN hydrogen […]
