Autores: de Souza, M. V. N.; Facchinetti, V.; Aboud, K. C. L.; da Penha, L. B.; Gomes, C. R. B. Source: Conjecturas, v. 22, p. 1657-5830, 2022 Publisher: Conjecturas Abstract The drug repurposing strategy is widely used by the pharmaceutical industry nowadays. This strategy is
Authors:Ribeiro, C. A.; Dos Reis, D. B.; Reis, I. F.; De Carvalho, A. N.; Lourenço, M. C. S.; De Souza, M. V. N.; Pinheiro, A. C.; Saraiva, M. F. Source: Medicinal Chemistry Research, v. 31, p. 949-959, 2022 Publisher: Springer Abstract In this work, we
Authors: Gomes, L. R.; Früchtl, H.; Low, J. N.; MOURIK, T.; Pinheiro, A. C.; De Souza, M. V. N.; Wardell, J. L. Source: Zeitschrift für anorganische und allgemeine Chemie (ZAAC), v. e, p. 1-9, 2022 Publisher: ZAAC Abstract The 2-hydrazinyl-1,3-benzothiazole derivatives are precursors for synthesis
Authors: Chazin, E. ; Martins, L.; De Souza, M. V.; Gomes, C. R.; Da Silva, A. C.; Branco, M.; Sanchez, E.; Fuly, A.; Vasconcelos, T. Source: Journal of the Brazilian Chemical Society, v. 33, p. 2-12, 2022 Publisher: SciELO Abstract This work describes the synthesis
[:pb]Authors: Tan, S. L. ; Cardoso, L. N. F. ; De Souza, M. V. N. ; Wardell, S. M. S. V. ; Wardell, J. L. ; Tiekink, E. R. T. Source: CrystEngComm, v. 24, p. 962-974, 2022 Publisher: Royal Society of Chemistry Abstract Parallel, offset
[:pb] Authors: Silva, E.T.; Santos, L. S.; Andrade, G. F.; Rosa, E. J. R.; De Souza, M. V. N. Source: Molecular Diversity, v. 26, p. 3463-3483, 2022 Publisher: Springer Abstract The development of new drugs requires a lot of time and high financial investments. It
[:pb]Authors: Nogueira, T. C. M. ; De Souza, M. V. N. Source: Bioorganic & Medicinal Chemistry, v. 46, p. 116340, 2021. Publisher: ScienceDirect Abstract In 2020, fifty-three new drugs, including forty small-molecules (thirty-six new chemical entities and four new diagnostic agents) and thirteen biologic drugs
[:pb]Authors: Nogueira, T. C. M.; De Souza, M. V. N. Source: Current Green Chemistry, v. 8, p. 99-126, 2021 Publisher: Bentham Science Publishers Abstract Five- and six-membered N-heterocyclic compounds play an important role in medicinal chemistry and the development of new drugs. There is a
[:pb]Authors: Facchinetti, V. ; Gomes, C. R. B. ; De Souza, M. V. N. Source: Tetrahedron, v. 102, p. 132544, 2021 Publisher: ScienceDirect Abstract The importance of 5-membered azaheterocycles is well established, especially in the medicinal chemistry field, as these nuclei are present in many
[:pb]Authors: Costa, C.F. ; De Souza, M. V. N. ; Facchinetti, V. ; Gomes, C. R. B. Source: General Chemistry, v. 7, p. 210004, 2021 Publisher: General Chemistry Abstract This work describes the synthesis of piperazine hydrochloride in multigram scale and high yields with promising
[:pb]Authors: Costa, G. O.; Facchinetti, V. ; Bezzera, M. S. ; Gomes, C.R.B ; De Souza, M. V. N. Source: Brazilian Journal of Development, v. 7, p. 48138-48146, 2021 Publisher: Brazilian Journal of Development Abstract Acrylic acid derivatives are important chemicals found in cosmetics, coatings,
[:pb]Authors: Da Silva, E. T. ; De Andrade, G. F. ; Araújo, A. S. ; Lourenço, M. C. S. ; De Souza, M. V. N. Source: European Journal of Pharmaceutical Sciences, v. 157, p. 105596, 2021. Publisher: ScienceDirect Abstract Objectives: The emergence of resistant strain
Nosso grupo de pesquisa está situado em Farmanguinhos e atualmente é o maior laboratório farmacêutico oficial vinculado ao Ministério da Saúde. Farmanguinhos produz mais de um bilhão de medicamentos por ano para os programas estratégicos do Governo Federal, além de atender demandas emergenciais no Brasil e no exterior.
